WebJan 26, 2024 · C-ImmSim server was implemented to examine the immune response against the designed multi-epitope antigen. Results and discussion: The designed chimeric vaccine construct included 21 immunodominant epitopes (six B-cell, eight cytotoxic T lymphocyte, and seven helper T-lymphocyte) and is predicted non-allergen, antigenic, … WebMulti Epitopic Peptide Based Vaccine Development Targeting Immobilization Antigen of Ichthyophthirius multifiliis: A Computational Approach
In-silico design of a multi-epitope vaccine candidate …
WebC-IMMSIM page GETTING HELP: Correspondence : Filippo Castiglione (filippo dot castiglione at cnr dot it) TERMS OF USE: This tool is provided "free to use for all". It is a … WebJul 8, 2024 · In the present study, the C-ImmSim server was used to simulate immune response with the candidate vaccine construct. Simulation with this tool focuses on B-cell epitope binding, class I and II HLA epitope binding, and the binding of the T-cell receptor to HLA-peptide complexes [ 47 ]. patco stations for parade
Frontiers Evaluation of the consistence between the results of ...
WebMay 11, 2024 · Results obtained from the C-IMMSIM server showed higher levels of IgM, IgM + IgG, IgG1 + IgG2, and IgG1 in secondary and tertiary immune responses. Antigen levels decreased at each level of immune response with the rise in antibody level (Fig. 3a). The decline in antigen levels imputes a rise in total B cell and T cell counts (Fig. 3c, d, e, f). WebA whole proteome of C. freundii (strain: CWH001) was retrieved to screen pathogenic and nonhomologous proteins. Six proteins were shortlisted for the selection of putative epitopes for vaccine ... WebMar 2, 2024 · C-ImmSim is an agent-based model that uses a position-specific scoring matrix (PSSM) for immune epitope forecast and machine … pat coy obituary