WebAs major regulators of the cell cycle, apoptosis and differentiation, E2F transcription factors have been studied extensively in a broad range of organisms. The recent identification of atypical E2F family members further expands our structural, functional and molecular view of the cellular E2F activity. Unlike other family members, atypical E2Fs … WebTo elucidate the epigenetic maintenance mechanism for functional plant centromeres, we studied transcriptional regulation of the centromere-specific histone H3 variant CENH3 in Arabidopsis thaliana. We focused on the structure and activity of the CENH3 promoter (CENH3pro) and its regulation by E2F transcription factors.Use of CENH3pro::GUS …
The E2F Family of Transcription Factors from Arabidopsis …
WebThe transcription factor E2F, the principal target of the tumor suppressor pRB, plays crucial roles in cell proliferation and tumor suppression. In almost all cancers, pRB function is disabled, and E2F activity is enhanced. To specifically target cancer cells, trials have been undertaken to suppress enhanced E2F activity to restrain cell proliferation or selectively … WebNov 12, 2007 · E2F proteins are a family of transcription factors that play a key role in regulation of the cell cycle, DNA replication and development in both animals and plants … small towns in california by the beach
(PDF) E2F-DP transcription factors - ResearchGate
WebMar 22, 2002 · The E2F transcription factors are key components of the cyclin D/retinoblastoma/E2F pathway. Here we demonstrate thatArabidopsis thaliana contains … WebNov 1, 2002 · The coordinated function of cell-cycle genes is essential for cell division and differentiation in all eukaryotes, including higher plants 1., 2., 3..Among the various cell-cycle regulators, e2f (see Glossary) transcription factor and the retinoblastoma (rb) repressor are the key players; their deregulation causes tumour formation in mammals … WebSep 1, 2004 · A Unique Subfamily of E2F/DP Transcription Factors in Plants and Animals. Completion of the Arabidopsis genome sequencing led to the identification of three novel members of the E2F/DP family of transcription factors that have received different names (De Jager et al., 2001; Kosugi and Ohashi, 2002a; Mariconti et al., 2002; Vandepoele et … hignia cordova facebook