Web14 nov. 2024 · Purpose For the first-line treatment of KRAS mutant non-small cell lung cancer (NSCLC) patients, immunotherapy or platinum-based chemotherapy are the main treatment method. Here, we investigated the clinical efficacy and prognosis those two regimens as first-line treatment in real-world practice. Methods KRAS mutant NSCLC … Web18 okt. 2024 · For many years, researchers have been trying to develop the most effective ways to fight lung cancer, which is the cause of the largest number of cancer-related deaths among men and women worldwide. The most advanced treatments for nearly all non-small-cell lung cancer (NSCLC) types include immunotherapy with immune checkpoint …
Efficacy of immunotherapy as second-line or later-line therapy and ...
Web2 dagen geleden · The U.S. National Comprehensive Cancer Network (NCCN) NSCLC guidelines recommend molecular testing for 11 driver mutations for which targeted … Web27 jun. 2024 · For KRAS, we still use immunotherapy as first-line therapy. Recent data from our group and others have suggested that if KRAS occurs in the setting of the second mutation in a tumor... spices the peninsula manila
KRAS G12C Mutations in NSCLC: From Target to Resistance
WebObjective: In this retrospective study, we aimed to assess the relationship between mutations in the Kirsten rats sarcoma viral oncogene (KRAS)/ tumor protein p53 (TP53) genes and the efficacy of immune checkpoint inhibitors (ICIs) therapy as a second-line or later-line treatment for patients with stage IIIB/IV non-small cell lung cancer (NSCLC). Web11 jul. 2024 · The current treatment paradigm for KRAS G12C -mutated lung patients, outside of a clinical trial, is standard frontline therapy, which is usually chemotherapy with immunotherapy in the frontline ... Web19 aug. 2024 · Programmed cell death receptor ligand-1 (PD-L1) expression, KRAS (KRASm) and EGFR (EGFRm) mutations may influence non-small cell lung cancer … spices to add to chicken